Sphingolipids in Major Depression
نویسندگان
چکیده
منابع مشابه
Sphingolipids in Major Depression.
Major depression is one of the most common and severe diseases affecting the world's population. However, the pathogenesis of the disease remains inadequately defined. Previously, a lack of monoaminergic neurotransmitters was the focus of pathophysiological concepts; however, recent concepts focus on a alteration of neurogenesis in the hippocampus. This concept suggests that neurogenesis is dec...
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Background: Major depression is a common disorder with great social and individual burdens. Transcranial sonography (TCS) is a useful and noninvasive measure for assessment of normal and impaired brain parenchyma. The brainstem raphe nuclei are in close association with dorsocaudal limbic system and plays an important role in depression. In this study we compared the echogenicity of the r...
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There are contradictory data regarding the levels of magnesium in patients with major depression (MD) and how antidepressants influence their concentration. Our results show erythrocyte magnesium in patients with MD (44.39 +/- 2.7 mg/L vs. 59.1 +/- 3.2 mg/L in control group, p < 0.05) and only in patients with severe MD (Hamilton score > 23) was a moderate decrease in plasmatic magnesium observ...
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OBJECTIVE To overview limitations to the concept and construct of major depression. METHOD The objectives in initially conceptualizing major depression are examined against its subsequent utility and relevance to clinicians and researchers. RESULTS It is argued that, as defined, major depression does not differentiate clinical depression well from expressions of non-clinical depression or s...
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ژورنال
عنوان ژورنال: Neurosignals
سال: 2015
ISSN: 1424-862X,1424-8638
DOI: 10.1159/000442603